Vyhledat publikace
Urban, M.; Frydrych, I.; Borková, L.; Hajdúch, M.; Vránová, B.
Triterpenes with inhibitory activity on Hedgehog signaling pathway for use in treatment of cancer
patent , 309885 , Úřad Průmyslového Vlastnictví, 2023.
Borková, L.; Frydrych, I.; Vránová, B.; Jakubcová, N.; Lišková, B.; Gurská, S.; Džubák, P.; Pavliš, P.; Hajdúch, M.; Urban, M.
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
Eur. J. Med. Chem. 2022, 244 (N/A), 114850. DOI: 10.1016/j.ejmech.2022.114850
Hodoň, J.; Frydrych, I.; Trhlíková, Z.; Pokorný, J.; Borková, L.; Benická, S.; Vlk, M.; Lišková, B.; Kubíčková, A.; Medvedíková, M.; Pisár, M.; Sarek, J.; Das, V.; Ligasová, A.; Koberna, K.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid pyrazines and pyridines – synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
Eur. J. Med. Chem. 2022, 243 (N/A), 114777. DOI: 10.1016/j.ejmech.2022.114777
Borková, L.; Frydrych, I.; Jakubcová, N.; Adámek, R.; Lišková, B.; Gurská, S.; Medvedíková, M.; Hajdúch, M.; Urban, M.
Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid
Eur. J. Med. Chem. 2020, 185 (N/A), Article Number: UNSP 111806 (1-18). DOI: 10.1016/j.ejmech.2019.111806
Urban, M.; Hodoň, J.; Borková, L.; Pokorný, J.; Kazakova, A.; Frydrych, I.; Gurská, S.; Řehulka, J.; Hajdúch, M.
Transformations of lupane triterpenes in the position C-30: synthesis, cytotoxic activity, SAR
XV. DDPEO 2019, November 25 – 27, 2019, Olomouc (Czech Republic), přednáška .
Borková, L.; Gurská, S.; Lišková, B.; Hajdúch, M.; Urban, M.
Triterpenoid thiazoles: from design and synthesis to in vitro biological evaluation
XV. DDPEO 2019, November 25 – 27, 2019, Olomouc (Czech Republic), přednáška .
Frydrych, I.; Borková, L.; Gurská, S.; Hajdúch, M.; Urban, M.
Cytotoxic triterpenoid thiazoles induce apoptosis in CCRF-CEM cells via disruption of mitochondria
XV. DDPEO 2019, November 25 – 27, 2019, Olomouc (Czech Republic), přednáška .
Hodoň, J.; Borkova, L.; Pokorny, J.; Kazakova, A.; Urban, M.
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research
Eur. J. Med. Chem. 2019, 182 (N/A), Article Number: 111653 (1-25). DOI: 10.1016/j.ejmech.2019.111653
Pokorný, J.; Borková, L.; Urban, M.
Click Reactions in Chemistry of Triterpenes – Advances Towards Development of Potential Therapeutics
Current Med. Chem. 2018, 25 (5), 636-658. DOI: 10.2174/0929867324666171009122612
Borková, L.; Hodoň, J.; Urban, M.
Synthesis of Betulinic Acid Derivatives with Modified A‐ring and their Development as Potential Drug Candidates
Asian J. Org. Chem. 2018, 7 (N/A), N/A. DOI: 10.1002/ajoc.201800163